PRMT7 DEFICIENCY CAUSES DYSREGULATION OF THE HCN CHANNELS IN THE CA1 PYRAMIDAL CELLS AND IMPAIRMENT OF SOCIAL BEHAVIORS

PRMT7 deficiency causes dysregulation of the HCN channels in the CA1 pyramidal cells and impairment of social behaviors

Neuroscience: Finding the brakes in the autistic brain Disrupted expression of an ion channel that helps stabilize brain Tool Boxes cell activity contributes to behavioral symptoms in mice resembling those seen in autism spectrum disorders (ASDs).Nerve cell firing depends on the right balance of ions inside and outside cells, and a channel protein

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Effect of corm planting density, organic and chemical fertilizers on formation and phosphorus uptake of saffron (Crocus sativus L.) replacement corms during phonological stages

Saffron (Crocus sativus L.) propagates by replacement corms producing from the mother corm after flowering during each season.In order to investigate the effect of corm planting density, organic and chemical fertilizers on formation and phosphorus uptake of saffron replacement corms during phonological stages, a field experiment was conducted as fa

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MacP bypass variants of Streptococcus pneumoniae PBP2a suggest a conserved mechanism for the activation of bifunctional cell wall synthases

ABSTRACTThe peptidoglycan (PG) layer protects bacteria from osmotic lysis and defines their shape.The class A penicillin-binding proteins (aPBPs) are PG synthases that possess both glycan polymerization and crosslinking activities needed for PG biogenesis.In Gram-negative bacteria, aPBPs require activation by outer membrane lipoproteins, which are

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